Scientific - Research Scientist
Job #: 24-02672
Pay Rate: Not Specified
Job type: contractor
Location: Seattle, WA
Pay Rate: Not Specified
Job type: contractor
Location: Seattle, WA
Top Skills:
• In-depth experience with developing ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).
• PhD >1 year relevant industry experience preferred.
• Experience in data review and experimental design/method development (e.g., 96-well plate map layouts).
The Scientist will independently develop and execute plate-based assays in support of process development as well as for characterization and release of autologous and allogenic cell therapies which are undergoing clinical trials, including CAR T cell products. The Scientist will be able to design and analyze experiments with some oversight that leads to the development of robust analytical methods. The Scientist will have the responsibility for developing highly impactful methods, including QC methods for lot release testing, as well as characterization methods that support process development and comparability assessments. These methods will be used for further understanding of cell therapies, support development of the manufacturing processes, and/or QC release of the drug product. The Scientist will have hands-on experience in ligand binding/antibody assay development and will be interested in projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC. The Scientist will be passionate about developing Client medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of like-minded Scientists.
Education: PhD in Biology, Immunology, Cancer Biology, or related field
Experience
• PhD >1 year relevant industry experience.
• In-depth experience with developing ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).
• Proven experience with data analysis and interpretation using software (e.g., Softmax Pro, Gen5, MSD Workbench, Excel).
• Experience in experimental design/method development (e.g., 96-well plate map layouts).
• Outstanding written and oral communication skills.
• Work effectively in a collaborative team setting.
• Ability to work in a rapidly changing environment with frequent changes in priorities, flexible.
• In-depth experience with developing ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).
• PhD >1 year relevant industry experience preferred.
• Experience in data review and experimental design/method development (e.g., 96-well plate map layouts).
The Scientist will independently develop and execute plate-based assays in support of process development as well as for characterization and release of autologous and allogenic cell therapies which are undergoing clinical trials, including CAR T cell products. The Scientist will be able to design and analyze experiments with some oversight that leads to the development of robust analytical methods. The Scientist will have the responsibility for developing highly impactful methods, including QC methods for lot release testing, as well as characterization methods that support process development and comparability assessments. These methods will be used for further understanding of cell therapies, support development of the manufacturing processes, and/or QC release of the drug product. The Scientist will have hands-on experience in ligand binding/antibody assay development and will be interested in projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC. The Scientist will be passionate about developing Client medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of like-minded Scientists.
Education: PhD in Biology, Immunology, Cancer Biology, or related field
Experience
• PhD >1 year relevant industry experience.
• In-depth experience with developing ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).
• Proven experience with data analysis and interpretation using software (e.g., Softmax Pro, Gen5, MSD Workbench, Excel).
• Experience in experimental design/method development (e.g., 96-well plate map layouts).
• Outstanding written and oral communication skills.
• Work effectively in a collaborative team setting.
• Ability to work in a rapidly changing environment with frequent changes in priorities, flexible.